2025-26 Men’s March Madness Odds: Duke Emerges as New Favorite

The college basketball regular season is winding down, but there’s still no clear favorite for which team will cut down the final net. 

Here’s a look at the odds for the NCAA Tournament winner at DraftKings Sportsbook as of March 5.

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2025-26 Men’s NCAA Tournament winner 

Duke: +320 (bet $10 to win $42 total)
Michigan: +330 (bet $10 to win $43 total)
Arizona: +475 (bet $10 to win $57.50 total)
Florida: +800 (bet $10 to win $90 total)
Houston: +1000 (bet $10 to win $110 total)
UConn: +1600 (bet $10 to win $170 total)
Illinois: +1700 (bet $10 to win $180 total)
Iowa State: +2200 (bet $10 to win $230 total)
Kansas: +3500 (bet $10 to win $360 total)
Purdue: +4000 (bet $10 to win $410 total)
Michigan State: +4000 (bet $10 to win $410 total)
Gonzaga: +5500 (bet $10 to win $560 total)
Arkansas: +6000 (bet $10 to win $610 total)
Alabama: +7000 (bet $10 to win $710 total)

Here’s what to know about the NCAA college hoops title oddsboard:

The Favorites: Duke is officially the favorite. Despite a 5-point loss to Duke on Feb. 21, the Wolverines were still favored to win it all earlier this week, with the Blue Devils second on the board. However, Duke remained the No. 1 team in the country, and had done nothing since that win over Michigan to negatively affect its position, blasting Notre Dame by 44 and blowing out Virginia by 26. Now, the odds are reflecting that dominance, as conference tournaments and the NCAA tournament inch closer.

Steady Falling: A couple squads whose odds have moved in the wrong direction are Houston and Illinois. Just over a week ago, the Cougars were at +750, but have dropped to +1000, after recently enduring a three-game losing streak — falling at Iowa State and Kansas, and at home against Arizona. However, only one of those teams is above them on the oddsboard, and that is the Wildcats. As for Illinois, it recently suffered back-to-back losses, at UCLA and at home against Michigan.